Publications by authors named "Emmanuel K A Amewu"
Lymphatic filariasis (LF) is a mosquito-borne neglected tropical disease that is one of the leading global causes of permanent disability. To date, LF interventions have been largely biomedical, focusing on drug treatments to disrupt parasite transmission and manage disease morbidity. Although important, these Mass Drug Administration (MDA) programs neglect the significance of socio-economic burden to the health of LF patients, which are compounded by social stigmatization, discrimination and associated depressive illnesses.
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- - Filarial infections affect over 150 million people in tropical regions, often causing lymphedema, which alters immune responses and could change the behavior of skin bacteria in affected individuals.
- - A study conducted in Ghana analyzed 160 lymphedema patients by taking samples from their ulcers and skin to test for antibiotic resistance, revealing high resistance rates to multiple antibiotics, including chloramphenicol and tetracycline.
- - Results showed that a significant portion of bacteria isolated from these patients were methicillin-resistant, indicating that treating infections in lymphedema patients may be challenging due to reduced effectiveness of antibiotics.
Background: Antimicrobial resistance is associated with increased morbidity in secondary infections and is a global threat owning to the ubiquitous nature of resistance genes in the environment. Recent estimate put the deaths associated with bacterial antimicrobial resistance in 2019 at 4.95 million worldwide.
View Article and Find Full Text PDFBackground: Lymphatic Filariasis (LF), a neglected tropical disease, has been speculated to be complicated by secondary bacteria, yet a systematic documentation of these bacterial populations is lacking. Thus, the primary focus of this study was to profile bacteria diversity in the progression of filarial lymphedema among LF individuals with or without wounds.
Methods: A cross-sectional study design recruited 132 LF individuals presenting with lymphedema with or without wounds from eight communities in the Ahanta West District in the Western Region, Ghana.
Background: Human lymphatic filarial pathology is the leading cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the disease's morbidity to improve patients' quality of life. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana.
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