Self-reported high-risk behavior among first-time and repeat replacement blood donors; a four-year retrospective study of patterns.

Background: There is no replacement for blood, and patients requiring transfusion depend on human donors, most of whom are family donors. Family donors may deny engagement in high-risk activities, which threaten the safety of donated blood. This study determined frequency of self-reported high-risk behaviors among replacement donors.

A Computational Approach to Elucidate the Interactions of Chemicals From Targeted Toward SARS-CoV-2 Main Protease Inhibition for COVID-19 Treatment.

The inhibitory potential of , a well-known antimalarial herb, against several viruses, including the coronavirus, is increasingly gaining recognition. The plant extract has shown significant activity against both the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the novel SARS-CoV-2 that is currently ravaging the world. It is therefore necessary to evaluate individual chemicals of the plant for inhibitory potential against SARS-CoV-2 for the purpose of designing drugs for the treatment of COVID-19.

Spices Mixture Containing Garlic, Ginger and Nutmeg Has Protective Effects on the Kidneys and Liver of Cadmium Exposed Rats.

Purpose: To determine the potential protective effect of spice mixture containing garlic, ginger and nutmeg on the liver and kidney of cadmium exposed rats.

Methods: Male albino rats (n=30) weighing 120 - 180 g, grouped into five (1-5) of 6 rats/group were studied. Group 1 (NC) rats were administered distilled water (1 ml) orally for 4 weeks and served as the negative control while group 2 (PC) rats were administered low dose (LD) cadmium (25 mg/kg body weight) orally for 4 weeks and served as positive control.

Plasma cadmium and zinc and their interrelationship in adult Nigerians: potential health implications.

Zinc (an essential trace element) and cadmium (a ubiquitous environmental pollutant with acclaimed toxicity) have been found to occur together in nature, with reported antagonism between the two elements. The present study aimed at determination of plasma levels of zinc (Zn) and cadmium (Cd) and their interrelationship in adult Nigerians. The series comprised adults (n=443) aged ≥18 yrs (mean ± SD 38.

Anaemia in Relation to Body Mass Index (BMI) and Socio-Demographic Characteristics in Adult Nigerians in Ebonyi State.

Introduction: Anaemia, a multifactorial health challenge has been found to affect every stage of human development with negative health impacts. Providing information on the factors associated with Anaemia will help in formulating mitigating strategies against this important public health problem.

Objective: To determine the prevalence of Anaemia and its relationship with body mass index (BMI) and sociodemographic characteristics in adult Nigerians in Ebonyi State, South-eastern Nigeria.

Cadmium-induced toxicity and the hepatoprotective potentials of aqueous extract of jessiaea nervosa leaf.

Purpose: Hepatoprotective potentials of Jussiaea nervosa leaf extract against Cadmium-induced hepatotoxicity were investigated.

Methods: Forty albino rats were randomly assigned into groups A-G with 4 rats in each of the groups A-F. Group A served as control and were given feed only while rats in groups B-F were orally exposed to varying concentrations of cadmium for six weeks.