Evaluation of the in vivo antimalarial activity of ethanolic leaf and stembark extracts of Anthocleista djalonensis.

Objective: To evaluate the in vivo antimalarial activities of ethanolic leaf and stembark extracts of Anthocleista djalonensis used traditionally as malarial remedy in Southern Nigeria in mice infected with Plasmodium berghei berghei.

Methods: The ethanolic extracts of the A. djalonensis leaf (1000 - 3000 mg/kg/day) and stembark (220 - 660 mg/kg/day) were screened for blood schizonticidal activity against chloroquine-sensitive P.

Antiplasmodial and antidiabetic activities of ethanolic leaf extract of Heinsia crinata.

The ethanolic leaf extract of Heinsia crinata, grown particularly for the leaf in Niger Delta region of Nigeria, was evaluated for antiplasmodial activity in Plasmodium berghei-infected mice as well as for hypoglycemic and antidiabetic activities in alloxan-induced diabetic rats. H. crinata (450-1,350 mg/kg/day) exhibited significant (P < .