PET-CT outcomes from a randomised controlled trial of rosuvastatin as an adjunct to standard tuberculosis treatment.

Adjunctive rosuvastatin for rifampicin-susceptible pulmonary tuberculosis (rs-PTB) shows no effect on microbiological or radiological outcomes in a phase IIb randomised, controlled trial (NCT04504851). We explore the impact of adjunctive rosuvastatin on 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) imaging in a sub-study of 24 participants. Changes in standardised uptake value (SUVmax, SUVmean), Total Metabolic Volume, (TMV), Total Lesion Glycolysis (TLG), cavity diameter and volume, between week 0 and week 8 post-randomisation, are evaluated.

Rosuvastatin adjunctive therapy for rifampicin-susceptible pulmonary tuberculosis: a phase 2b, randomised, open-label, multicentre trial.

Background: Shorter treatments are needed for drug-susceptible tuberculosis. Adjunctive statins increase bactericidal activity in preclinical tuberculosis models. We investigated the safety and efficacy of adjunctive rosuvastatin in people with tuberculosis.

Cyanide-Free Copper-Silver Electroplated Coatings on Carbon Steel Exposed to 5% NaClO Bleacher.

This work deals with the development of cyanide-free copper-silver electroplated coatings on AISI-1075 steel and its corrosion behavior under a 5% NaClO solution (commercial household bleach). A cyanide-free bath based on sodium thiosulfate was employed to obtain the silver coatings using current densities from 0.2 to 5.

Raw data of silver extraction from sodium-silver jarosite using three different lixiviants in alkaline medium.

This article presents the raw data of silver concentration ([Ag]) obtained as a function of time (t) from silver leaching experiments, which were conducted using a synthetic sodium-silver jarosite and different complexing agents: thiosulfate, thiocyanate, and cyanide. Leaching experiments were performed under different conditions of temperature, pH and lixiviant concentration. The data refer to the article "Silver leaching from jarosite-type compounds using cyanide and non-cyanide lixiviants: a kinetic approach" (Islas et al.

Thallium(I) sequestration by jarosite and birnessite: Structural incorporation vs surface adsorption.

Jarosite and birnessite secondary minerals play a pivotal role in the mobility, transport and fate of trace elements in the environment, although geochemical interactions of these compounds with extremely toxic thallium (Tl) remain poorly known. In this study, we investigated the sorption behavior of Tl(I) onto synthetic jarosite and birnessite, two minerals commonly found in soils and sediments as well as in mining-impacted areas where harsh conditions are involved. To achieve this, sorption and desorption experiments were carried out under two different acidic conditions and various Tl(I) concentrations to mimic natural scenarios.

Solid-phase distribution and mobility of thallium in mining-metallurgical residues: Environmental hazard implications.

Thallium (Tl) and its compounds are non-essential and highly toxic for living organisms, even at low concentrations. In this paper, we analyzed the presence and geochemical distribution of Tl in different mining-metallurgical and sediment samples collected from several mining zones of Mexico. A modified BCR sequential extraction procedure was also applied to the samples to investigate the geochemical behavior and potential environmental risk of Tl according to types of ore deposit and mineral processing method applied.