Publications by authors named "Emmanuel G Christodoulou"

Background: Neurointerventional procedures represent a significant source of ionizing radiation. We sought to assess the effect during neurointerventional procedures of varying default rates of radiation dose in fluoroscopy (F) and image acquisition (IA) modes, and frame rates during cine acquisition (CINE) on total X-ray dose, acquisition exposures, fluoroscopy time, and complications.

Methods: We retrospectively reviewed procedures performed with two radiation dose and CINE settings: a factory setting dose cohort (30 patients, F 45 nGy/pulse, IA 3.

View Article and Find Full Text PDF

A new approach to the problem of environmental hazard assessment and monitoring for pollutant biodegradation reaction systems in the presence of uncertainty is proposed using soft sensor-based pollutant concentration dynamic profile reconstruction techniques. In particular, a robust reduced-order soft sensor is proposed that can be digitally implemented in the presence of inherent complexity and the inevitable model uncertainty. The proposed method explicitly incorporates all the available information associated with a process model characterized by varying degrees of uncertainty, as well as available sensor measurements of certain physicochemical quantities.

View Article and Find Full Text PDF

Purpose: To retrospectively compare image quality and radiation dose between a reduced-dose computed tomographic (CT) protocol that uses model-based iterative reconstruction (MBIR) and a standard-dose CT protocol that uses 30% adaptive statistical iterative reconstruction (ASIR) with filtered back projection.

Materials And Methods: Institutional review board approval was obtained. Clinical CT images of the chest, abdomen, and pelvis obtained with a reduced-dose protocol were identified.

View Article and Find Full Text PDF

Purpose: This study was performed to investigate the accuracies of the synthesized monochromatic images and effective atomic number maps obtained with the new GE Discovery CT750 HD CT scanner.

Methods: A Gammex-RMI model 467 tissue characterization phantom and the CT number linearity section of a Phantom Laboratory Catphan 600 phantom were scanned using the dual energy (DE) feature on the GE CT750 HD scanner. Synthesized monochromatic images at various energies between 40 and 120 keV and effective atomic number (Z(eff)) maps were generated.

View Article and Find Full Text PDF

Calcium concentration may be a useful feature for distinguishing benign from malignant lung nodules in computer-aided diagnosis. The calcium concentration can be estimated from the measured CT number of the nodule and a CT number vs calcium concentration calibration line that is derived from CT scans of two or more calcium reference standards. To account for CT number nonuniformity in the reconstruction field, such calibration lines may be obtained at multiple locations within lung regions in an anthropomorphic phantom.

View Article and Find Full Text PDF

The new NCRP Report No. 147 includes methodology to determine x-ray protective shielding for CT scanner rooms. This methodology assumes fixed values of the scatter fraction per centimeter (kappa) for the peripheral axis of the head and body CT phantoms.

View Article and Find Full Text PDF

A study was performed to determine the accuracies and reproducibilities of the CT numbers of simulated lung nodules imaged with multi-detector CT scanners. The nodules were simulated by spherical balls of three diameters (4.8, 9.

View Article and Find Full Text PDF

A study was conducted to evaluate the radiation transmission through lead equivalent aprons that are used in a radiology department. A large area beam (poor geometry) was employed for the transmission measurements, and backscatter was simulated by placing 7" of Lucite behind each apron. Separate ionization chambers were used to measure the incident and transmitted x-ray beams.

View Article and Find Full Text PDF