Publications by authors named "Emmanuel Boateng"

Heteroatom doping has been widely recognized as a key strategy for improving the electrochemical properties of graphene-based materials for hydrogen storage. However, a precise understanding of how heteroatom doping influences catalytic performance, specifically regarding the intricate effects of doping-induced electron redistribution, has been lacking. Here, we report on a comprehensive exploration of the electrochemical performance enhancement in Pd-decorated reduced graphene oxide (rGO) nanocomposites through fluorine (F) or nitrogen (N) doping.

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Background: Clonal hematopoiesis of indeterminate potential (CHIP) occurs due to acquired mutations in bone marrow progenitor cells. CHIP confers a 2-fold risk of atherosclerotic cardiovascular disease. However, there are limited data regarding specific cardiovascular phenotypes.

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Cardiovascular disease is one of the leading causes of premature death worldwide, and the determination of C-reactive protein (CRP) from human serum is of vital importance for the diagnosis of the disease. For this study, we have developed an electrochemical immunosensor based on onion-like carbon@polyacrylonitrile (OLC-PAN) for the detection of CRP antigens. This was accomplished by immobilizing CRP antibodies on a modified glassy carbon electrode (GCE).

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Background: Hypertension is a major risk factor for cardiovascular diseases. Insights and foresights on trends of hypertension prevalence are crucial to informing health policymaking. We examined and projected the patterns of hypertension prevalence among sexes.

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Hydrogen is a promising green fuel carrier that can replace fossil fuels; however, its storage is still a challenge. Carbon-based materials with metal catalysts have recently been the focus of research for solid-state hydrogen storage due to their efficacy and low cost. Here, we report on the exfoliation of expanded graphite (EG) through high shear mixing and probe tip sonication methods to form graphene-based nanomaterial ShEG and sEG, respectively.

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Background: Crohn's Disease (CD) is an inflammatory disease of the gastrointestinal tract that affects millions of patients. While great strides have been made in treatment, namely in biologic therapy such as anti-TNF drugs, CD remains a significant health burden.

Method: We conducted two meta-analyses using our STARGEO platform to tag samples from Gene Expression Omnibus.

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Article Synopsis
  • Hepatitis B virus (HBV) can lead to liver cancer (hepatocellular carcinoma) through oncogenic processes, not just cirrhosis, highlighting the need to identify specific genes and pathways involved.
  • The study aims to better understand how HBV contributes to liver cancer and to find potential therapeutic targets using a meta-analysis of tumor and adjacent non-tumor samples.
  • Key findings include the identification of RABL6 and HOXA10 as significant regulators in HBV-related liver cancer, with RABL6 linked to increased mortality and HOXA10 implicated in tumor growth through mechanisms like downregulation of tumor suppressors.
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4-hydroxy-3-methoxybenzaldehyde (vanillin) is a biophenol compound that is relatively abundant in the world's most popular flavoring ingredient, natural vanilla. As a powerful antioxidant chemical with beneficial antimicrobial properties, vanillin is not only used as a flavoring agent in food, beverages, perfumery, and pharmaceutical products, it may also be employed as a food-preserving agent, and to fight against yeast and molds. The widespread use of vanilla in major industries warrants the need to develop simple and cost-effective strategies for the quantitative determination of its major component, vanillin.

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The influence of soil properties on PFOS sorption are not fully understood, particularly for variable charge soils. PFOS batch sorption isotherms were conducted for 114 temperate and tropical soils from Australia and Fiji, that were well-characterized for their soil properties, including total organic carbon (TOC), anion exchange capacity, and surface charge. In most soils, PFOS sorption isotherms were nonlinear.

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Aims: To examine and forecast the patterns of diabetes prevalence in synergy with obesity.

Methods: Prophet models were employed to forecast the prevalence of diabetes and obesity in 2030 using time-series data from the WHO Global Health Observatory data repository. K-means clustering models and self-organising maps were used to identify the patterns (clusters) of diabetes prevalence in association with obesity among 183 countries.

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Graphene is an attractive soft material for various applications due to its unique and exclusive properties. The processing and preservation of 2D graphene at large scales is challenging due to its inherent propensity for layer restacking. Three-dimensional graphene-based nanomaterials (3D-GNMs) preserve their structures while improving processability along with providing enhanced characteristics, which exhibit some notable advantages over 2D graphene.

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Neuregulin-1β (NRG-1) is a membrane-bound or secreted growth and differentiation factor that mediates its action by binding to ErbB receptors. Circulating levels of NRG-1 are characterized by large inter-individual variability with the range of absolute values covering two orders of magnitude, from hundreds to tens of thousands of picograms per milliliter of blood. NRG-1 signaling via ErbB receptors contributes to the cell survival and downregulation of the inflammatory response.

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The World Health Organization (WHO) has highlighted the beneficial role of adequate intake of potassium (K) in combating the global burden of noncommunicable diseases (NCDs), mainly hypertension and cardiovascular diseases. Diets are the main source of K supply to humans and can contribute to both K deficiency (hypokalemia) and excess (hyperkalemia). While global attention is currently devoted to K deficiency, K excess can be even more dangerous and deserves equal attention.

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Adequate dietary intake of potassium (K) helps fight noncommunicable diseases (NCDs), mainly hypertension and cardiovascular diseases. This paper (i) estimated the K intake of Ghanaian population using food supply and food composition data and (ii) compared this estimate with the WHO recommended requirement for K in order to assess if there is a risk of inadequate K intake. Food supply data (1961-2011) was obtained from the FAO Food Balance Sheet (FBS) to derive trends in food and K supply.

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