The experience of pain in real-time during medication abortion.

Objective: We aimed to characterize the current pain experience of patients completing an evidence-based mifepristone-misoprostol medication abortion regimen using real-time pain scores.

Study Design: We collected real-time data on pain experienced by 54 women undergoing medication abortion using an evidence-based regimen of 200 mg mifepristone and 800 mcg buccal misoprostol. These women were enrolled in the placebo arm of a study on the effect of pregabalin for pain during medication abortion.

Text message link to online survey: A new highly effective method of longitudinal data collection.

Objectives: To evaluate response rate to a text message link for an online survey as a method of data collection over the course of a medication abortion.

Study Design: This is a secondary analysis of a randomized, double-blind, placebo-controlled trial of 110 women initiating a medication abortion up to 70 days gestation. We sent a text message containing a link to an online survey collecting pain scores, analgesic use, and adverse effects at six time points over 72 h from time of misoprostol administration (0-, 2-, 6-, 12-, 24-, and 72-hours).

Prophylactic Pregabalin to Decrease Pain During Medication Abortion: A Randomized Controlled Trial.

Objective: To evaluate whether prophylactic pregabalin reduces pain experienced with medication abortion.

Methods: We conducted a randomized, double-blind, placebo-controlled trial of women initiating medication abortion with mifepristone and buccal misoprostol up to 70 days of gestation. Participants were randomized to 300 mg oral pregabalin or a placebo immediately before misoprostol.