Publications by authors named "Emma Y Li"
Article Synopsis
- Juvenile hormone (JH) and 20-hydroxyecdysone (20E) are crucial for regulating insect development and metamorphosis, with two receptors (Met and Gce) identified in fruit flies.
- By studying phosphoproteome profiles in a double mutant lacking these receptors, researchers explored how JH works through a membrane signaling pathway without intracellular interference.
- The findings revealed that JH activates protein kinase C (PKC) to phosphorylate ultraspiracle (USP) at a specific site, enhancing 20E signaling, which is vital for normal fly development and growth.
Juvenile hormone (JH) regulates insect development and reproduction through both intracellular and membrane signaling, and the two pathways might crosstalk with each other. Recent studies have reported that JH membrane signaling induces phosphorylation of the JH intracellular receptor Met, thus enhancing its transcriptional activity. To gain more insights into JH-induced Met phosphorylation, we here performed phosphoproteomics to identify potential phosphorylation sites of Met and its paralog Germ-cell expressed (Gce) in Kc cells.
View Article and Find Full Text PDFThe Drosophila melanogaster corpus allatum (CA) produces and releases three types of sesquiterpenoid hormones, including juvenile hormone III bisepoxide (JHB3), juvenile hormone III (JH III), and methyl farnesoate (MF). JH biosynthesis involves multiple discrete enzymatic reactions and is subjected to a comprehensive regulatory network including microRNAs (miRNAs). Using a high throughput sequencing approach, we have identified abundant miRNAs in the D.
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