Publications by authors named "Emma Stepinac"
Article Synopsis
- Extended synaptotagmins (E-Syts) help with lipid transfer and maintaining lipid balance between the endoplasmic reticulum and plasma membrane.
- TbE-Syt is a newly identified, unique E-Syt in a protist parasite that only has two C2 domains, making it the shortest known E-Syt.
- The crystal structure analysis of TbE-Syt-C2B shows it can bind to lipids with calcium and PI(4,5)P, while C2A, lacking a calcium-binding site, may still interact with lipids differently, suggesting a method for lipid transfer between the ER and plasma membrane.
The duplication and ninefold symmetry of the centriole requires that the cartwheel molecule, Sas6, physically associates with Gorab, a trans-Golgi component. How Gorab achieves these disparate associations is unclear. Here, we use hydrogen-deuterium exchange mass spectrometry to define Gorab's interacting surfaces that mediate its subcellular localization.
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