Implementation of HIV Preexposure Prophylaxis in a Homeless Primary Care Setting at the Veterans Affairs.

Oral preexposure prophylaxis (PrEP) is highly effective in preventing HIV-1 acquisition, yet it is underutilized among at-risk populations. In this pilot quality improvement (QI) initiative, we sought to identify barriers to PrEP implementation and create interventions to improve access to PrEP in a primary care clinic for homeless veterans. The setting was a large homeless primary care clinic at the Veterans Affairs in an urban area with high HIV prevalence.