Publications by authors named "Emma I Kopra"

Background: Psychedelic drugs are increasingly visible in society once more, but their risks and adverse effects have received less attention than perhaps they should. While fatalities associated with psychedelics appear rare, a systematic approach to characterising their aetiology is required to inform harm minimisation efforts.

Aims: This study aimed to analyse prevalence and characteristics of psychedelic-related deaths in England, Wales, and Northern Ireland, between 1997 and 2022.

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Article Synopsis
  • Impulsivity is higher in individuals with psychosis and mania compared to those without, and research aims to determine if this trait is inherited from family members of those with bipolar disorder or schizophrenia.
  • A systematic review and meta-analysis evaluated 19 studies, revealing that relatives of individuals with bipolar disorder exhibited significantly greater impulsivity compared to controls, while relatives of those with schizophrenia did not show significant differences.
  • The findings suggest that impulsivity might be an endophenotype for bipolar disorder, indicating a potential early risk factor for developing the disorder, and further research is needed to better measure impulsivity and understand its components in at-risk individuals.
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Background: Growing numbers of people are using psychedelics for personal psychotherapy outside clinical settings, but research on such use is scarce.

Aims: This study investigated the patterns of use, self-reported outcomes and outcome predictors of psychedelic 'self-treatment' of mental health conditions or specific worries/concerns in life.

Methods: We use data from the Global Drug Survey 2020, a large online survey on drug use collected between November 2019 and February 2020.

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Background: Psychedelic therapy shows promise for Major Depressive Disorder, especially when treatment-resistant, as well as life-threatening illness distress. The objective of this systematic review, inclusive of meta-analysis, is to examine recent clinical research on the therapeutic effects of classic psychedelics on depressive symptoms.

Methods: Fourteen psychedelic therapy studies, utilising psilocybin, ayahuasca, or LSD, were systematically reviewed.

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Background: Recreational lysergic acid diethylamide (LSD) use is growing in popularity amid increasing research interest on psychedelics and their possible therapeutic potential yet; the potent psychotropic effects of LSD may result in adverse reactions and behaviour.

Aims: This study aimed to investigate the 12-month incidence and nature of LSD-related adverse experiences resulting in emergency medical treatment (EMT) seeking in an international sample of people reporting LSD use.

Methods: We use data from the 2017 Global Drug Survey - a large anonymous online survey on patterns of drug use conducted between November 2016 and January 2017.

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Background: Psilocybin-containing mushrooms are used for recreational, spiritual, self-development and therapeutic purposes. However, physiologically relatively nontoxic, adverse reactions are occasionally reported.

Aims: This study investigated the 12-month prevalence and nature of magic mushroom-related adverse reactions resulting in emergency medical treatment seeking in a global sample of people reporting magic mushroom use.

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