Biomed Instrum Technol
May 2018
The capping layer stabilizing silver nanoparticles (AgNPs) affects its aggregation, dissolution, and net disinfection action, especially under conditions of varying water composition, such as, pH, ionic strength and organic matter content. Herein, we correlate the silver ion (Ag(+)) release and reactive oxygen species (ROS) generation rates for AgNPs of varying functionalization to their net disinfection coefficient on Escherichia coli, under conditions of differing water chemistries. For electrostatically stabilized citrate-capped AgNPs, the rate of ROS generation, as measured using a fluorescent dye, is found to dominate over that of Ag(+) release, especially for smaller sized AgNP suspensions (~10nm) at low pH (~6.
View Article and Find Full Text PDFThis article introduces a method to identify risks through expert elicitation, using silver nanotechnology as a case study. Unique features of the method include supplying experts with a list of silver nanotechnology products, and conducting the elicitation in an extended interview format that captures the experts' reasoning. The end result is a series of graphical representations of expert thinking from which high-risk scenarios and knowledge gaps can be reliably inferred.
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