Synopsis of recent research by authors named "Emma E Cawood"
- Emma E Cawood's research primarily focuses on understanding protein-protein interactions (PPIs) and their implications in biological processes and diseases, particularly utilizing intrinsically disordered sequences and the role of peptide modifications in enhancing binding specificity.
- Significant findings include the effective modification of peptide backbones to tune binding behaviors in PPIs, the development of bioorthogonal approaches for synthesizing homogeneous glycoproteins, and insights into the dynamic oligomerization of chaperone proteins like DNAJB6 in the context of neurodegenerative diseases.
- Cawood's studies emphasize the importance of transient oligomers and intermediates in amyloid assembly pathways, exploring their role in diseases such as amyloidosis and developing methods to visualize and manipulate these critical species for potential therapeutic strategies.*
