Publications by authors named "Emma E Brown"

Article Synopsis
  • Megalin (Lrp2) is a crucial receptor in the kidneys that helps reclaim important proteins like albumin, and its absence affects various cellular processes, including SGLT2 expression.
  • Deleting Lrp2 in opossum kidney cells led to a significant drop in SGLT2 levels and altered gene expression linked to metabolism and mitochondrial function, while Lrp2 knockout mice showed better glucose tolerance on high-fat diets.
  • Interestingly, male Lrp2 KO mice faced kidney damage from a Western-style diet, whereas female counterparts showed less susceptibility, indicating a complex relationship between megalin, diet, and metabolic health.
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HIV testing for some African American men remains a challenge, and effective interventions are lacking. We explored facilitators and barriers associated with HIV testing among heterosexual African American men in rural Florida. We conducted focus group interviews with 67 African American men who were low-income, and HIV-uninfected based on prior testing or had unknown HIV status.

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Purpose: In the United States, black/African American (black) men bear the greatest burden of human immunodeficiency virus (HIV), accounting for 42% of new HIV infections in 2012 despite being 6% of the population. In Florida, heterosexual HIV transmission has increased among black men. Few studies have examined HIV testing experiences for black heterosexual men (BHM) in the rural South.

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Object: The aim in this paper was to localize and detect incipient damage to the ophthalmic and maxillary branches of the trigeminal nerve during tumor surgery.

Methods: This was an observational study of patients with skull base, retroorbital, or cavernous sinus tumors warranting dissection toward the cavernous sinus at a university hospital. Stimuli were applied as normal during approach to the cavernous sinus to localize cranial nerves (CNs) III, IV, and VI.

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In Florida, the HIV case rate among black men is five times that of white men; tailored HIV prevention interventions are lacking. Historical concerns regarding trust with public health venues and sharing sensitive information make face-to-face data collection with some rural, southern black men challenging. We evaluated the feasibility and acceptability of using audio computer-assisted self-interviews (ACASIs) by local community-based organization members to collect HIV-related information from black men in rural settings.

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