Publications by authors named "Emma D Stephens"
Article Synopsis
- - Biofluid-contacting devices often experience biofouling, leading to issues like thrombus formation and bacterial biofilm buildup, which negatively affect device performance and health safety.
- - Traditional antifouling solutions like hydrophilic polymers and heparin coatings are usually unstable, while lubricant-infused surfaces (LIS) offer better long-term effectiveness but are complicated to produce and limited in application.
- - This study presents a new approach for creating flexible lubricant-infused poly(vinyl alcohol) (PVA) membranes that exhibit excellent antifouling properties and improved mechanical flexibility, potentially enhancing the performance of medical devices and implants by reducing blood clots and bacterial adhesion.
Due to organ donor shortages, long transplant waitlists, and the complications/limitations associated with auto and allotransplantation, biomaterials and tissue-engineered models are gaining attention as feasible alternatives for replacing and reconstructing damaged organs and tissues. Among various tissue engineering applications, bone tissue engineering has become a promising strategy to replace or repair damaged bone. We aimed to provide an overview of bioactive ceramic scaffolds in bone tissue engineering, focusing on angiogenesis and the effect of different biofunctionalization strategies.
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- * Bacterial nanocellulose (BNC) is a promising biocompatible material for blood-contacting applications, known for its high porosity and tissue-like qualities, making it suitable for artificial vascular grafts.
- * Various techniques have been developed to modify BNC, such as chemical treatments and structural adjustments, to enhance its hemostatic properties and mechanical strength, crucial for improving its performance in biomedical uses.
Bacterial nanocellulose (BNC) is a naturally derived hydrogel that has recently paved its way in several biomedical applications. Despite its remarkable tissue-like properties, BNC does not express innate anticoagulant or antimicrobial properties; therefore, appropriate post-modification procedures are required to prevent nonspecific adhesion and enhance the hemocompatibility properties of BNC-based biointerface. Here, we report a new class of flexible, lubricant-infused BNC membranes with superior antithrombotic and antibacterial properties.
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