Publications by authors named "Emma Cuadro Alvarez"
Objectives: This cross-sectional study aimed to investigate the influence of haplotypes, alpha-gene status and UGTA1 polymorphism on the severity of sickle cell disease in children.
Methods: This cross-sectional study was conducted between 2012 and 2014 at the Cayenne Hospital, in French Guiana. Acute clinical complications were grouped into (i) severe SCD defined by the presence of stroke and/or abnormal-transcranial Doppler (TCD), (ii) moderate SCD defined by the presence of at least three annual events requiring hospitalization and/or at least one acute chest syndrome, (iii) no severe SCD (in the absence of the precited events).
Acute encephalitis is an important cause of mortality and morbidity in children. We retrospectively identified children (≤15 years of age) admitted with suspected encephalitis at the Intensive Care Unit of the Pediatric Department of Cayenne Hospital between January 2007 and December 2018. A total of 30 children with acute encephalitis were identified.
View Article and Find Full Text PDFBackground: This study aims to describe the predictive factors of severe obesity in children followed in French Guiana.
Methods: In this observational study, the patients from the French Guianese Childhood Obesity Group database were prospectively included, after giving a statement of patient's non opposition.
Results: Our group classifications revealed that 36 of 150 (24%) participants were classified as being metabolically abnormal obesity" (MAO), while 114 of 150 (76%) were categorized as metabolically normal obesity" (MNO).
Article Synopsis
- A 10-year-old boy from Brazil developed eosinophilic meningitis and transverse myelitis after traveling to Suriname, linked to the parasitic infection Angiostrongylus cantonensis.
- Diagnosis was confirmed through serological tests and real-time PCR analysis of his cerebrospinal fluid.
- It's crucial for the medical community to recognize angiostrongyliasis as a potential health concern in the Guiana Shield region.*
The incidence of dengue worldwide is increasing rapidly. A better understanding of dengue transmission may help improve interventions against this major public health problem. The virus is mostly transmitted by vectors.
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- The study focused on understanding the occurrence of infantile Pompe disease (IPD) in French Guiana, particularly within the African-American Maroon community.
- Over a 13-year period, 19 newborns were identified with IPD, indicating an incidence rate of 1 in 4528 births, significantly higher in the Maroon population.
- Genetic analysis showed that all affected infants had mutations linked to the disease, suggesting a double founder effect due to the community's limited genetic diversity.
Article Synopsis
- Infants under 3 months with fever often face serious bacterial infection risks, leading to a study on Chikungunya during the 2014-2015 outbreak at Cayenne Hospital.
- A total of 120 infants were hospitalized, with 26 diagnosed with Chikungunya, showing symptoms like high fever, irritability, and skin rash; notable, 15% also had serious bacterial infections.
- The study suggests that specific symptoms and high PCT levels can help identify infants at risk for Chikungunya, emphasizing the need for more extensive research to confirm these findings.
In order to determine the predictive value of a rash during dengue fever, a cohort study was conducted in children hospitalized for dengue during an epidemic in French Guiana. A rash was predictive of uncomplicated dengue: the HR of developing a severe form of disease was 0.43 (95% CI 0.
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