Publications by authors named "Emma C Lipinski"
Article Synopsis
- Fluorosubstituted tryptophans, like 7-fluoro-tryptophan, are useful in studying proteins through fluorescence and NMR techniques.
- In cyclophilin A, UV exposure of 7-fluoro-tryptophan leads to the creation of a bright fluorophore by crosslinking with nearby phenylalanine, achieving a high quantum yield and fluorescence lifetime.
- This study is the first to document a Phe-Trp crosslink in a protein, potentially paving the way for new fluorescence probes and methods to utilize aromatic crosslinks in protein research.
