Publications by authors named "Emma B Saxon"

The predatory bacterium grows and divides inside the periplasm of Gram-negative bacteria, forming a structure known as a bdelloplast. Cell division of predators inside the dead prey cell is not by binary fission but instead by synchronous division of a single elongated filamentous cell into odd or even numbers of progeny cells. replication and cell division processes are dependent on the finite level of nutrients available from inside the prey bacterium.

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Background: 30-day mortality might be a useful indicator of avoidable harm to patients from systemic anticancer treatments, but data for this indicator are limited. The Systemic Anti-Cancer Therapy (SACT) dataset collated by Public Health England allows the assessment of factors affecting 30-day mortality in a national patient population. The aim of this first study based on the SACT dataset was to establish national 30-day mortality benchmarks for breast and lung cancer patients receiving SACT in England, and to start to identify where patient care could be improved.

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Background: Pseudomonas tolaasii is a problematic pathogen of cultured mushrooms, forming dark brown 'blotches' on mushroom surfaces and causing spoilage during crop growth and post-harvest . Treating P. tolaasii infection is difficult, as other, commensal bacterial species such as Pseudomonas putida are necessary for mushroom growth, so treatments must be relatively specific.

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Article Synopsis
  • Bdellovibrio bacteriovorus uses Type IV pili (T4P) for invading Gram-negative bacteria and locates prey by gliding on surfaces.
  • The absence of the mglB gene in Bdellovibrio impacts the function of MglA(Bd), crucial for prey-invasion and T4P formation, although gliding remains unaffected.
  • Key proteins like Bd2492, RomR, and CdgA work at the invasive pole to regulate MglA, facilitating the predatory growth of Bdellovibrio by enabling it to invade and kill bacteria.
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