Antibacterial Activities of Pyrenylated Coumarins from the Roots of Prangos hulusii.

The dichloromethane extract of the roots of , a recently described endemic species from Turkey, has yielded nine known and one new prenylated coumarins. The structures were elucidated by spectroscopic methods and direct comparison with the reference compounds where available. The root extract and its prenylated coumarins exhibit antimicrobial activity against nine standard and six clinically isolated strains at a concentration between 5 and 125 µg/mL.