Publications by authors named "Emir Berberovic"
J Neural Transm (Vienna)
November 2024
Article Synopsis
- Botulinum neurotoxin (BoNT) has been utilized since the 1970s, primarily by blocking acetylcholine release in motor neurons and associated areas to affect muscle movement.
- It is increasingly being used to treat various motor and non-motor symptoms of Parkinson's disease, sometimes becoming the preferred treatment for specific symptoms.
- The text aims to summarize the indications for BoNT use, its potential side effects, and the regulatory approvals for its therapies addressing both primary and secondary symptoms of Parkinson's disease.
Article Synopsis
- Multiple system atrophy (MSA) presents in two main forms: MSA-P with Parkinson's symptoms and MSA-C with cerebellar issues, both causing impaired dexterity.
- The study compared brain imaging and dexterity performance between MSA patients and healthy controls to understand how different degeneration patterns contribute to motor difficulties.
- Results show cerebellar degeneration affects dexterity in both MSA types, indicating it may be a useful biomarker for tracking disease progression, while nigrostriatal degeneration showed no significant impact on dexterity.
