Publications by authors named "Emine Nedime Korucu"
Gene expression of MTATP6 and cytochrome P450 in MCF-7 and MDA-MB -231 breast cancer cell lines with juglone and curcumin supplemented.
Nucleosides Nucleotides Nucleic Acids
October 2024
Article Synopsis
- The study investigates the effects of naphthoquinones, specifically juglone and curcumin, on cell viability and gene expression in two human breast cancer cell lines, MCF-7 and MDA-MB-231.
- Both compounds were tested at various concentrations over a 24-hour period, with results measured using qPCR and western blot techniques.
- The findings indicated that curcumin and juglone reduced the expression of the CYP3A4 and MTATP6 genes in both cell lines, with curcumin also displaying anti-proliferative and antioxidant properties.