HIIT serves as an efficient training strategy for basketball players by improving blood fluidity and decreasing oxidative stress.

Background: A challenge for coaches and athletes is to find the best combination of exercises during training. Considering its favorable effects, HIIT has been very popular recently.

Objective: The goal of this study was to investigate anthropometric features, performance, erythrocyte deformability, plasma viscosity (PV) and oxidative stress in response to acute and long-term (6 weeks) HIIT in adolescent basketball players.

Effects of Autologous Serum and Platelet-Rich Plasma on Human Corneal Endothelial Cell Regeneration: A Comparative Study.

Objectives: To investigate the effects of autologous serum (AS) and platelet-rich plasma (PRP) on human corneal endothelial cell (HCEC) proliferation and apoptosis in comparison to Y-27632 as the commonly studied Rho-associated kinase (ROCK) inhibitor.

Methods: The human corneal endothelial primary cell line was used for this study. As the treatment groups, HCECs were incubated with AS, PRP, and Y-27632, whereas the control group received no treatment.

Investigation of fructose consumption on hippocampal insulin and glucagon-like peptide-1 receptors, and metabolic effects in rats.

Objectives: The detrimental effects of high fructose consumption on metabolic health have been extensively studied. However, limited research has focused on the impact of fructose intake on neuroprotective mechanisms, specifically the expression of insulin receptor (INSR) and glucagon-like peptide-1 receptor (GLP-1R) in the hippocampus. Understanding the effects of fructose on these neuroprotective molecules can provide valuable insights into the potential role of fructose in hippocampal dysfunction.

Swimming exercise restores damaging effects of fructose-enriched diet on the liver in rats.

Fructose-enriched diet (FED) is increasing worldwide. The study aims to investigate oxidative, histopathological, and immunohistochemical effects of fructose-enriched diet and swimming exercise on liver tissue in rats. Wistar rats were divided into 4 groups: Group I (Control), Group II (FED), Group III (FED+Exercise), and Group IV (Control+Exercise).

Verbascoside potentiates the effect of tyrosine kinase inhibitors on the induction of apoptosis and oxidative stress via the Abl-mediated MAPK signalling pathway in chronic myeloid leukaemia.

Verbascoside (Verb) may exhibit potential antitumour activities in leukaemia. The present study investigated the effect of Verb, in combination with imatinib (IM), dasatinib (Das), lipopolysaccharide (LPS) and TNF, on cell survival, Abl expression, apoptosis, oxidative stress and the MAPK pathway in chronic myeloid leukaemia (CML) cells. Cell viability was determined using the WST-8 assay in K562 and R-K562 cells treated with Verb and/or IM, Das, LPS and TNF.

Investigating the Activity of Indole-2-on Derivative Src Kinase Inhibitors Against Chronic Myeloid Leukemia Cells.

Background: Src family tyrosine kinases play a potential role in Bcr-Abl-induced leukemogenesis. Src kinase inhibitors are reported as selective inhibitors of chronic myeloid leukemia.

Objective: Since Src kinase inhibitors have an inhibitive effect on chronic myeloid leukemia, indole derivatives (C-1, C-2, C-3) previously found as potent inhibitors of Src kinase were tested against chronic myeloid leukemia in this study.

Hemorheology and oxidative stress in patients with differentiated thyroid cancer following I-131 ablation/metastasis treatment.

Background: Although radioiodine theraphy (RAIT) is thought to affect blood cells and oxidative stress, hemorheological alterations following dose-dependent RAIT remains unknown.

Objective: The aim of this study was to determine the effects of RAIT on hemorheological and oxidative stress parameters in patients with differentiated thyroid cancers (DTC).

Methods: Totally 31 DTC patients (mean age 46.

Oxidative Stress and Genotoxicity in Pterygium: A Systemic Investigation.

Objectives: To perform a systemic investigation on oxidative stress and DNA damage in patients with primary pterygium.

Methods: This prospective cross-sectional study included 32 patients with primary pterygium (60.1±2.

Increased erythrocyte aggregation following an acute bout of eccentric isokinetic exercise does not exceed two days.

Background: Isokinetic exercise is used to reduce strength imbalance and to enhance performance.

Objective: The aim of this study was to investigate the acute effects of a single bout of eccentric isokinetic exercise on hemorheology (erythrocyte deformability and aggregation), total oxidant/antioxidant status (TOS/TAS) and oxidative stress index (OSI) in active individuals.

Methods: The study comprises 11 active, healthy, male subjects (mean age of 19.

Hemorheological alterations following an acute bout of nordic hamstring exercise in active male participants1.

Background: The Nordic hamstring exercise (NHE) has been proven to be an effective preventive technique for hamstring injuries. Hemorheological parameters (erythrocyte deformability and aggregation) play a critical role in exercise influencing oxygenation. Although previous studies presented hemorheological alterations induced by different types of exercise, changes in red blood cell (RBC) deformability and aggregation following NHE remain unknown.

Impaired Blood Rheology in Pulmonary Arterial Hypertension.

Background: Understanding of the pathophysiologic manifestations of pulmonary arterial hypertension (PAH) is still evolving. The aims of the present study were to determine the alterations in blood rheology, and to investigate the relationship between those alterations and laboratory parameters in PAH.

Methods: The study included 21 consecutive treatment-naive patients with PAH and 32 age and sex-matched healthy controls.

Contribution of Heme Oxygenase 2 to Blood Pressure Regulation in Response to Swimming Exercise and Detraining in Spontaneously Hypertensive Rats.

BACKGROUND We aimed to determine the effects of exercise followed by detraining on systolic blood pressure (SBP), heme oxygenase 2 (HO-2) expression, and carboxyhemoglobin (COHb) concentration in spontaneously hypertensive rats (SHR) to explain the role of carbon monoxide (CO) in this process. MATERIAL AND METHODS Animals were randomized into exercised and detrained groups. Corresponding sedentary rats were grouped as Time 1-2.

Impaired Hemorheology in Exacerbations of COPD.

Background: Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation. Cardiovascular-related comorbidities are established to contribute to morbidity and mortality especially during exacerbations. The aim of the current study was to determine alterations in hemorheology (erythrocyte aggregation, deformability) in newly diagnosed COPD patients and their response to medical treatment and to compare with values of COPD patients with exacerbations.

Hemorheological dysfunction in cardiac syndrome X.

Background: Cardiac syndrome X (CSX) is often described as angina or angina-like chest pain with a normal coronary arteriogram, yet the underlying pathophysiological mechanisms have not been fully elucidated. The aim of the current study was to determine alterations in blood rheology (erythrocyte aggregation and deformability, plasma viscosity - PV) in patients with CSX.

Methods: The study comprised 26 CSX patients (55.

Increased erythrocyte aggregation and oxidative stress in patients with idiopathic interstitial pneumonia.

Background: Hemorheological properties are important determinants of tissue oxygenation. Although hemorheological alterations in various lung diseases have been well-defined, no information is available about the effects of idiopathic interstitial pneumonia (IIP) on hemorheological parameters.

Objectives: The aim of this study was to investigate hemorheological parameters (erythrocyte deformability, aggregation, and plasma viscosity -PV) and associated oxidative stress indices in patients with IIP.

Increased erythrocyte aggregation in patients with primary open angle glaucoma.

Background: The rationale of this study is to determine alterations in blood rheology (erythrocyte aggregation and deformability) and relationship between structural measurements obtained from optical coherence tomography (OCT) in different stages of primary open angle glaucoma (POAG).

Methods: This prospective controlled study comprised 23 POAG patients (glaucoma group) and 23 age- and sex-matched healthy subjects (control group). Elongation index (EI), which is the indicator of erythrocyte deformability and erythrocyte aggregation was measured using an ektacytometer.

Impaired Hemorheological Parameters and Increased Carotid Intima-Media Thickness in Children with Subclinical Hypothyroidism.

Background: Subclinical hypothyroidism (SH) is defined as elevated serum thyroid-stimulating hormone (TSH) concentration associated with normal serum-free thyroxine levels. Effects of hypothyroidism on hemorheology had widely attracted the attention of researchers during the last decade.

Objective: The purpose of this study is to determine alterations in hemorheological parameters and carotid intima-media thickness (CIMT) in children with SH.

Detraining reverses exercise-induced improvement in blood pressure associated with decrements of oxidative stress in various tissues in spontaneously hypertensive rats.

This study aimed to investigate the effects of moderate intensity swimming exercise (10 weeks) followed by detraining (for five and 10 weeks) on oxidative stress levels of heart, lung, kidney, and liver tissues and systolic blood pressure (SBP) of spontaneously hypertensive rats (SHR). SHR and control rats were randomized into sedentary, exercised, detrained (5 weeks) and late-detrained (10 weeks) groups. Corresponding sedentary rats were grouped as time 1-2-3.

Acute effects of continuous and intermittent aerobic exercises on hemorheological parameters: a pilot study.

Background: Acute hemorheological responses to different types of aerobic exercises have never been compared in a single study in healthy people.

Objective: We aimed to compare acute effects of high intensity intermittent exercise (HIIE) and moderate intensity continuous exercise (MICE) on hemorheological parameters, in healthy young subjects.

Methods: A total of 34 sedentary young adults (12 males, 22 females) with a mean age of 20.

Exercise training and detraining modify hemorheological parameters of spontaneously hypertensive rats.

Background: Hemorheological responses to swimming exercise have never been investigated in spontaneously hypertensive rats (SHR).

Objective: We aimed to investigate the effects of moderate intensity swimming exercise followed by detraining on erythrocyte deformability and aggregation in SHR.

Methods: SHR and WKY rats were randomized into sedentary, exercised, detrained (5 weeks) and late detrained (10 weeks) groups.

Acute effects of Yo-Yo intermittent recovery test level 1 (Yo-YoIR1) on hemorheological parameters in female volleyball players.

In the present study, we investigated possible alterations in red blood cell (RBC) deformability, plasma and whole blood viscosities (WBV) and hematological parameters in response to Yo-Yo intermittent recovery test level 1 (Yo-YoIR1) which is currently used to assess endurance performance, in female volleyball players. Eight volleyball player volunteers from Pamukkale University (mean age19,9 ± 2,2 years; mean body height 177.5 ± 1.

Investigation of hemorheological parameters at the diagnosis and follow up of children with iron deficiency anemia and mixed anemia.

Objective: We aimed to investigate the effects of iron deficiency anemia (IDA) and vitamin B12 deficiency coexisting with IDA which is called as mixed anemia (MA) on hemorheological parameters, to compare them with each other and healthy controls, and to assess the changes in hemorheological parameters after treatment.

Materials And Methods: 32 IDA patients (mean age:6.3 ± 5.

The effect of L-carnosine on erythrocyte deformability and aggregation according to the cell age in young and aged rats.

This study aimed to investigate alterations in hemorheology induced by L-carnosine, an anti- oxidant dipeptide, and to determine their relationship to oxidative stress in density-separated erythrocytes of aged and young rats. 28 male Sprague Dawley rats were divided into 4 groups as aged (Aca), young (Yca) L-carnosine groups (250 mg/kg L-carnosine, i.p.

Investigation of hemorheological parameters at the diagnosis and the follow-up of nutritional vitamin B12 deficient children.

We aimed to investigate the effects of vitamin B12 deficiency on hemorheological parameters, and the changes in these parameters following vitamin B12 treatment. 33 patients (mean-age:7 ± 5.7 years) diagnosed as nutritional vitamin B12 deficiency, and 31 age and sex matched controls (mean-age:7.

Altitude training induced alterations in erythrocyte rheological properties: a controlled comparison study in rats.

Altitude training is frequently used by athletes to improve sea-level performance. However, the objective benefits of altitude training are controversial. This study aimed to investigate the possible alterations in hemorheological parameters in response to altitude training.