A fatal case of heparin-induced thrombocytopenia and thrombosis.

Heparin induced thrombocytopenia (HIT) is a significant, potentially life-threatening immune-mediated adverse event that occurs several days after commencement of therapy with unfractionated or low-molecular weight heparin. We present a 51-year-old female treated with unfractionated heparin for acute deep venous thrombosis (DVT) and pulmonary embolism (PE). She developed extension of her thrombosis and was promptly diagnosed with heparin-induced thrombocytopenia and thrombosis (HITT).