A randomized, single-dose, crossover study of the effects of ulotaront on electrocardiogram intervals in subjects with schizophrenia.

This study (NCT04369391) evaluated the effects of ulotaront (SEP-363856), a novel trace amine-associated receptor 1 (TAAR1) agonist in development for schizophrenia, on electrocardiogram parameters. Study design was a randomized, single-dose, three-period crossover (ulotaront 150 mg, placebo, moxifloxacin 400 mg). Sixty subjects with schizophrenia completed all periods.

Nursing delegation. Implications for home care.

Consumers are advocating for client-directed care and are influencing legislation that regulates delegation within nurse practice acts. Almost 18 months ago, the Visiting Nurse Association of Texas implemented the delegation of insulin administration for appropriate patients. Results indicate that the program is a success and the time invested in developing the program was well spent.