Publications by authors named "Emily R Morrison"
Carbohydr Res
November 2024
Article Synopsis
- The study discusses the effective and selective synthesis of iminosugars, specifically 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) and lentiginosine, focusing on their seven stereoisomers.
- The starting material for these syntheses is 4-benzoyl-6-deoxy-6-iodoglycopyranosides, yielding between 38% to 68% for DAB and between 44% to 89% for lentiginosine.
- A key highlight of the process is a complex multistep reaction involving zinc-mediated reductive elimination, reductive amination, and intramolecular nucleophilic substitution, which allows for the
