Concurrent Zoster Sine Herpete and Hepatosplenic Fungal Infection in a Cancer Patient: A Case Report.

In patients undergoing treatment for hematological cancers, like hairy cell leukemia (HCL), appropriate management of infections is of utmost importance. This paper describes the successful treatment of an HCL patient who had both visceral zoster sine herpete (ZSH) and hepatosplenic fungal infection, possibly caused by . To our knowledge, this is the first such case to appear in the literature, as these are rare conditions associated with states of immunosuppression, similar to those observed in hematological malignancy.

Cryoneurolysis of the saphenous nerve in the pig: A proof-of-principle investigation.

Objective: To determine if in vivo cryoneurolysis inhibits ex vivo compound action potential (CAP) conduction in the porcine saphenous nerve and if this occurs rapidly enough to justify performing the technique before stifle surgery.

Study Design: Blinded, controlled, randomized, preclinical study.

Animals: A group of eight healthy, 8 weeks old, intact, female pigs anesthetized for an unrelated terminal study.

Image analysis comparison of nerve staining with food dye, methylene blue or tissue marker.

Objective: Novel locoregional techniques use dye studies to confirm successful nerve targeting. The goal was to objectively quantify and compare nerve staining characteristics of dye mixtures commonly reported in the literature using image analysis software.

Study Design: Prospective, randomized cadaveric study.

A Clinical Scoring Systems for the Evaluation of -associated Disease in NSG Mice.

Clinical signs of infections are well-known in athymic nude mice. However, can also infect and cause clinical signs in many hirsute, immunocompromised mouse strains such as NSG (NOD. Cg-Prkdc Il2rg/SzJ).

Differences in autobiographical memories reported using text and voice during everyday life.

Autobiographical memories frequently occur during everyday life. One of the most common approaches to measuring memories in everyday life is a diary method: Participants record memories as they occur by writing down these memories in a paper diary or typing them on a smartphone. Conversely, many laboratory-based studies of autobiographical memory require participants to describe their memories out loud in a spoken manner.

Identification and evaluation of medication-related issues relating to patient's own drugs by pharmacy students while on placement in a tertiary hospital.

Background Pharmacy students require knowledge of prescribing and supply of medicines; this is achievable through work-based learning. In UK hospitals, pharmacy technicians assess patient's own drugs (PODs) so medicines can be used as they would be at home. Student-led POD checks have not yet been considered as an opportunity for legitimate peripheral participation (LPP).

Metaphylactic Antibiotic Treatment to Prevent the Transmission of to Immunocompromised Mouse Offspring.

Current methods for eradicating , such as depopulation, embryo transfer, and cesarean rederivation followed by cross fostering, are expensive, complex, and time-consuming. We investigated a novel method to produce immunocompromised offspring free of from infected NOD. Cg-PrkdcIl2rg/SzJ (NSG) breeding pairs.

A validation study of the International Trauma Questionnaire to assess post-traumatic stress disorder in treatment-seeking veterans.

Background: Veterans with post-traumatic stress disorder (PTSD) typically report a poorer treatment response than those who have not served in the Armed Forces. A possible explanation is that veterans often present with complex symptoms of PTSD. ICD-11 PTSD and complex PTSD (CPTSD) have not previously been explored in a military sample.

Crystal structure of a ligand-free stable TSH receptor leucine-rich repeat domain.

The crystal structures of the thyroid-stimulating hormone receptor (TSHR) leucine-rich repeat domain (amino acids 22-260; TSHR260) in complex with a stimulating human monoclonal autoantibody (M22TM) and in complex with a blocking human autoantibody (K1-70™) have been solved. However, attempts to purify and crystallise free TSHR260, that is not bound to an autoantibody, have been unsuccessful due to the poor stability of free TSHR260. We now describe a TSHR260 mutant that has been stabilised by the introduction of six mutations (H63C, R112P, D143P, D151E, V169R and I253R) to form TSHR260-JMG55TM, which is approximately 900 times more thermostable than wild-type TSHR260.

Effectiveness of Interventions for Children With Autism Spectrum Disorder and Their Parents: A Systematic Review of Family Outcomes.

This systematic review examined the literature published from January 2006 to April 2013 related to the effectiveness of occupational therapy interventions for children with autism spectrum disorder (ASD) and their parents to improve parental stress and self-efficacy, coping, and resilience and family participation in daily life and routines. From the 4,457 abstracts, 34 articles were selected that matched the inclusion criteria. The results were mixed and somewhat inconclusive because this body of literature is in its infancy.