The Effects of a Core Stabilization Training Program on the Performance of Functional Tasks in Firefighters.

The purpose of this study was to observe if core stabilization training plays a significant role in firefighter time-to-completion during a functional performance test. A within subjects study design was used in which subjects ( = 13, 84.6% male, 33.

Further defining the roles and impact of genetic counselors in the biotechnology and pharmaceutical industry.

As personalized medicine has gained traction, drug development models in the biotechnology and pharmaceutical industry (BPI) have increasingly sought to address medical conditions with a genetic component, creating an opportunity for genetic counselors (GCs) to fill new roles and utilize their unique training to contribute to drug development. Despite the potential for GCs in BPI, literature around the role of GCs in this industry has been limited. Our mixed methods study aimed to assess how the roles of GCs in BPI have evolved since 2016, investigate the value of and opportunity for GCs in this industry, and further characterize their motivation and job satisfaction.

Keeping It Organized: Multicompartment Constructs to Mimic Tissue Heterogeneity.

Tissue engineering aims at replicating tissues and organs to develop applications in vivo and in vitro. In vivo, by engineering artificial constructs using functional materials and cells to provide both physiological form and function. In vitro, by engineering three-dimensional (3D) models to support drug discovery and enable understanding of fundamental biology.

Treatment and outcome of childhood cerebral sinovenous thrombosis.

Objective: To test our hypothesis that anticoagulation is associated with better neurologic outcomes in childhood cerebral sinovenous thrombosis (CSVT), we analyzed treatment and outcomes in a population of 410 children from the International Pediatric Stroke Study (IPSS).

Methods: We included patients enrolled in the IPSS registry with a diagnosis of CSVT at age >28 days with radiologic confirmation, in isolation or with concomitant arterial ischemic stroke. The primary outcome was the neurologic status at discharge.

Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management.

Pediatric arterial ischemic stroke (AIS) is an uncommon but important cause of neurologic morbidity in neonates and children, with consequences including hemiparesis, intellectual disabilities, and epilepsy. The causes of pediatric AIS are unique to those typically associated with stroke in adults. Familiarity with the risk factors for AIS in children will help with efficient diagnosis, which is unfortunately frequently delayed.

Hemispheric lateralization of verbal and spatial working memory during adolescence.

Adult functional magnetic resonance imaging (fMRI) literature suggests that a left-right hemispheric dissociation may exist between verbal and spatial working memory (WM), respectively. However, investigation of this type has been obscured by incomparable verbal and spatial WM tasks and/or visual inspection at arbitrary thresholds as means to assess lateralization. Furthermore, it is unclear whether this hemispheric lateralization is present during adolescence, a time in which WM skills are improving, and whether there is a developmental association with laterality of brain functioning.

The impact of sex, puberty, and hormones on white matter microstructure in adolescents.

Background: During adolescence, numerous factors influence the organization of the brain. It is unclear what influence sex and puberty have on white matter microstructure, as well as the role that rapidly increasing sex steroids play.

Methods: White matter microstructure was examined in 77 adolescents (ages 10-16) using diffusion tensor imaging.

A different outlook on time: visual and auditory month names elicit different mental vantage points for a time-space synaesthete.

Synaesthesia is a fascinating condition whereby individuals report extraordinary experiences when presented with ordinary stimuli. Here we examined an individual (L) who experiences time units (i.e.

The ups and downs (and lefts and rights) of synaesthetic number forms: validation from spatial cueing and SNARC-type tasks.

Typically, numbers are spatially represented using a mental 'number line' running from left to right. Individuals with number-form synaesthesia experience numbers as occupying specific spatial coordinates that are much more complex than a typical number line. Two synaesthetes (L and B) describe experiencing the numbers 1 through 10 running vertically from bottom to top, 10-20 horizontally from left to right, 21-40 from right to left, etc.