Suspected Anaphylactic Reaction to Ketamine in 3 Yucatan Swine ().

This case series describes the clinical courses of 3 juvenile Yucatan miniature swine () that experienced a suspected anaphylactic reaction to ketamine hydrochloride during premedication for protocol-related surgery. All 3 swine rapidly developed diffuse erythema shortly after injection with ketamine-containing drug combinations. Clinical signs ranged from tachycardia and erythema alone to tachycardia and erythema followed by respiratory and cardiac arrest.