Real-world treatment patterns, healthcare resource use and disease burden in patients with multiple myeloma in Europe.

To investigate treatment patterns, healthcare resource utilization and disease burden in patients with multiple myeloma (MM). Point-in-time survey of physicians and their patients presenting in a real-world clinical setting, collected across Europe between May and November 2021. In total, 173 physicians provided data for 2179 patients with MM.

Drivers of physician decision-making and patient perspectives across lines of therapy in multiple myeloma in the USA.

To explore treatment selection for relapsed/refractory multiple myeloma (RRMM), which remains complex due to heterogeneity of available treatments and lack of defined standard of care. The Adelphi Real World MM Disease Specific Programme surveyed physicians in the USA and their patients with MM to collect real-world data on patterns and perceptions of MM treatment across lines of therapy (LOT). Triplets were the most common regimens across each LOT.

Real-world patient-reported outcomes and concordance between patient and physician reporting of side effects across lines of therapy in multiple myeloma within the USA.

Purpose: We aimed to explore patient-reported outcomes (PROs) and patient and physician concordance of side effects perception across lines of therapy (LOT) in multiple myeloma (MM) within the United States of America (USA).

Methods: Data were drawn from the Adelphi Real World MM III Disease Specific Programme™, a point-in-time survey of hemato-oncologists/hematologists and their patients with MM conducted in the USA between August 2020 and July 2021. Physicians reported patient characteristics and side effects.

Rapid sol-gel synthesis of honeycomb-layered NaNiBiO and orthorhombic NaCaBiO.

The AMM'O type materials NaCaBiO and NaNiBiO were successfully synthesised through two sol-gel techniques - a method based on a natural deep eutectic solvent, and a biopolymer-mediated synthesis. The materials were analysed using Scanning Electron Microscopy to determine if there was a difference in final morphology between the two methods, and it was found that the natural deep eutectic solvent method resulted in a more porous morphology. For both materials, the optimum dwell temperature was found to be 800 °C, which in the case of NaCaBiO was a much less energy-intensive synthesis process than its seminal solid-state synthesis.

Synthesis of porous high-temperature superconductors a melamine formaldehyde sacrificial template.

Nanostructured high-temperature superconductors YBaCuO and BiSrCaCuO were synthesised using a melamine formaldehyde sponge as a sacrificial template, three solution-based approaches. In the case of YBaCuO , a modified Pechini method produced a material with a superconducting transition at 92 K and a specific surface area of 4.22 m g.