Publications by authors named "Emily Laughlin"
Purpose: This study aimed to investigate the stability of the Gross Motor Function Classification System (GMFCS) in children with cerebral palsy (CP) in the two to four year age band, the frequency at which children were reclassified, and trends of reclassification to higher or lower ability.
Methods: This retrospective study included 164 children with CP between 24 to 48 months old with two or more GMFCS ratings at least 12 months apart between their second and fourth birthdays. GMFCS ratings were captured closest to 24, 36, and 48 months.
Everesting: cycling the elevation of the tallest mountain on Earth.
Eur J Appl Physiol
December 2022
Purpose: With few cycling races on the calendar in 2020 due to COVID-19, Everesting became a popular challenge: you select one hill and cycle up and down it until you reach the accumulated elevation of Mt. Everest (8,848 m or 29,029ft). With an almost infinite number of different hills across the world, the question arises what the optimal hill for Everesting would be.
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- Dosage compensation in C. elegans adjusts gene expression from X chromosomes in hermaphrodites to match that of XO males via the dosage compensation complex (DCC).
- The targeting of the DCC to the X chromosomes involves sequence motifs and chromatin environment factors, with HTZ-1 previously shown to affect DCC localization.
- Research identified DPY-30 as a key protein for DCC binding, revealing that while both DPY-30 and HTZ-1 are critical for DCC localization, their functions are independent of H3K4 methylation.