We formulate the maximum driving force (MDF) parameter as a descriptor to capture the thermodynamic stability of aqueous surface scale creation over a range of environmental conditions. We use free energies of formation, Δ's, sourced from high-throughput density functional theory (DFT) calculations and experimental databases to compute the maximum driving force for a range of materials, including oxides and hydroxides of varying compositions. We show how to use the MDF to describe trends in the aqueous corrosion of nickel thin films determined from experimental linear sweep voltammetry data.
View Article and Find Full Text PDFJ Pediatr Rehabil Med
October 2021
This case report details the complex rehabilitation of an adolescent patient with congenital heart disease with anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) who presented with a sudden cardiac arrest. The International Classification of Functioning, Disability and Health for Children and Youth, World Health Organization (ICF-CY WHO) principles were used to guide the course of the patient's acute inpatient rehabilitation.
View Article and Find Full Text PDFBackground: Sarcospan (SSPN) is a transmembrane protein that interacts with the sarcoglycans (SGs) to form a tight subcomplex within the dystrophin-glycoprotein complex that spans the sarcolemma and interacts with laminin in the extracellular matrix. Overexpression of SSPN ameliorates Duchenne muscular dystrophy in murine models.
Methods: Standard cloning approaches were used to identify nanospan, and nanospan-specific polyclonal antibodies were generated and validated.
There is currently wide variation in the use and cost of post acute care following total joint arthroplasty. Additionally the optimum setting to which patients should be discharged after surgery is controversial. Discharge patterns following joint replacement vary widely between physicians at our institution, however, only weak correlations were found between the cost of discharge and length of stay or readmission rates.
View Article and Find Full Text PDFInt J Shoulder Surg
October 2012
Aims: To assess whether patients above 50 years of age, particularly female, would benefit from repair of their SLAP tears.
Settings And Design: Review of patients' records followed by telephone interview at a minimum of two years after surgery.
Materials And Methods: Seventy-two consecutive patients who had their SLAP repaired were retrospective reviewed by an independent examiner.
Sarcospan is a component of the dystrophin-glycoprotein complex that forms a tight subcomplex with the sarcoglycans. The sarcoglycan-sarcospan subcomplex functions to stabilize alpha-dystroglycan at the plasma membrane and perturbations of this subcomplex are associated with autosomal recessive limb-girdle muscular dystrophy. In order to characterize protein interactions within this subcomplex, we first demonstrate that sarcospan forms homo-oligomers within the membrane.
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