Publications by authors named "Emily Krantz"
Aortic growth rates in a Swedish cohort of women with Turner syndrome.
Int J Cardiol Congenit Heart Dis
March 2024
Background: Aortic dilation, cardiac malformations and hypertension are known risk factors for aortic dissection in Turner syndrome (TS). In the current guidelines, rapid growth of the aorta has been added as a risk marker. This study aimed to estimate the growth of the ascending aorta over time, to identify risk factors of aortic growth, and to describe aortic complications in TS.
View Article and Find Full Text PDFTurner syndrome (TS) is a genetic condition characterized by partial or complete monosomy X. A reduced life expectancy has been shown in TS, depending on an increased risk of aortic dissection, and ischemic heart disease. Studies covering the occurrence of psychiatric conditions are sparse within TS.
View Article and Find Full Text PDFBackground: Teriparatide was the first anabolic agent recommended for the treatment of osteoporosis. Long-term real-world, controlled studies are not available. The purpose was to evaluate the long-term effects of treatment with teriparatide on fractures and Health Related Quality of Life in subjects with established osteoporosis in comparison with placebo treated patients with osteoporosis and the general population.
View Article and Find Full Text PDFArticle Synopsis
- Women with Turner syndrome (TS) face a higher risk of aortic dissection, and this study aimed to identify the most predictive aortic size measurements to help assess that risk.
- The research, involving 400 TS women in Sweden, found that absolute ascending aortic diameter (AAD) and a TS-specific z-score were much better at predicting aortic dissection risk compared to the current standard, the aortic size index (ASI).
- The study determined optimal cutoff values for AAD (3.3 cm) and TS z-score (2.12) that showed high sensitivity (92%), emphasizing the need for careful monitoring, especially during pregnancy.
Article Synopsis
- Obesity negatively affects health-related quality of life (HRQoL), leading individuals to report lower overall well-being compared to the general population.
- In a study involving 1,122 participants with obesity and a control group of 414 individuals, lower scores in physical and mental health aspects were noted among those with obesity.
- The findings suggest a higher prevalence of mental health issues and medication use among obese individuals seeking treatment, highlighting their greater struggle with both physical and mental well-being.
Hearing and balance deteriorate, and fracture incidence increases with age, especially in women. The aim of the present study was to investigate whether impaired hearing and body balance are stronger predictors of fractures than bone mass. Between 1995 and 1997, 80 women, aged 50 to 70 years, with primary osteoporosis, taking menopausal hormone therapy, mainly for menopausal symptoms, participated in a double-blind, randomized, placebo-controlled study of treatment with growth hormone versus placebo.
View Article and Find Full Text PDFObjective: Hypoparathyroidism (HypoPT) is a rare endocrine disorder in which insufficient levels of parathyroid hormone (PTH) lead to low serum calcium (S-Ca) levels and muscular cramps. The aim was to study the health-related quality of life (HRQoL) and comorbidities in patients with HypoPT compared with the general population and to estimate the need of treatment with PTH analog.
Design: Patients with HypoPT were identified and compared with a population sample.
Objective: To explore health-related quality of life (HRQoL) among subjects with hypothyroidism compared to subjects without hypothyroidism in the general population. HRQoL is important in clinical practice. Hypothyroidism is prevalent, mainly found in women, and increasing with age.
View Article and Find Full Text PDFTo explore the relationship between low serum vitamin D levels and comorbidity in Somali women, immigrants to Sweden. Cohort study in a Primary Health Care Center and a University Hospital. Somali women skin type V, n = 114, aged 18-56 years, from latitude 0-10 N, living in Sweden, latitude 57 N > 2 years were compared with women from a population sample, skin type II-III, n = 69, aged 38-56 years, the WHO MONICA study, Gothenburg, Sweden.
View Article and Find Full Text PDFContext: The factors that affect the health-related quality of life (HRQoL) of women with Turner syndrome (TS) are controversial.
Objective: The aim was to describe the HRQoL of women with TS with a focus on how given GH treatment and comorbidity influence HRQoL in adulthood and to compare HRQoL of women with TS with that of women in the general population.
Design: Longitudinal cohort study, up to 20 years.
Objective: The general aim was to meet the need for empirical comparative studies of health-related quality of life (HRQoL) assessment instruments, by evaluating and comparing the psychometric properties and results of three different, widely used, generic HRQoL instruments in a population sample. The specific aims were to evaluate the subscales of the different instruments that measure the same domain and to assess the association between the HRQoL measures and a single-item self-rated health scale.
Design: An observational cross-sectional study.
Context: Growth hormone (GH) treatment increases bone mineral density (BMD) in women with postmenopausal osteoporosis.
Objective: The objective was to report bone data, fractures, and quality of life (QoL) in a 10-year follow-up of women who had received GH for 3 years and compared with controls followed in parallel.
Design And Setting: A follow-up of a double-blind, placebo-controlled study conducted at Sahlgrenska University Hospital was performed.