Publications by authors named "Emily Kolaya"
Microorganisms typically used to produce food and pharmaceuticals are now being explored as medicines and agricultural supplements. However, maintaining high viability from manufacturing until use remains an important challenge, requiring sophisticated cold chains and packaging. Here we report synthetic extremophiles of industrially relevant gram-negative bacteria (Escherichia coli Nissle 1917, Ensifer meliloti), gram-positive bacteria (Lactobacillus plantarum) and yeast (Saccharomyces boulardii).
View Article and Find Full Text PDFEnergy-Efficient Ingestible Drug Delivery System in the Dynamic Gastrointestinal Environment.
Annu Int Conf IEEE Eng Med Biol Soc
July 2023
Article Synopsis
- Ingestible electronics offer new ways for health monitoring and drug delivery directly in the gastrointestinal (GI) tract, which has varying pH levels that can affect device performance.
- The presented system uses an electrochemically dissolvable gold membrane to control drug release, adapting to the GI environment's pH for optimized functionality.
- This innovative design not only enhances drug delivery efficiency by reducing energy consumption by up to 42.8%, but also allows for targeted therapeutic effects at various locations within the GI tract.
Deep brain stimulation: Challenges at the tissue-electrode interface and current solutions.
Biotechnol Prog
September 2021
Deep brain stimulation (DBS) is used to treat the motor symptoms of Parkinson's disease patients by stimulating the subthalamic nucleus. However, optimization of DBS is still needed since the performance of the neural electrodes is limited by the body's response to the implant. This review discusses the issues with DBS, such as placement of electrodes, foreign body response, and electrode degradation.
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