Impact of medication intensification on 30-day hospital readmissions in a geriatric trauma population: A multicenter cohort study.

Background: Fall-related injuries are a significant health issue that occur in 25% of older adults and account for a significant number of trauma-related hospitalizations. Although medication intensification may increase the risk of hospital readmissions in non-trauma patients, data on a geriatric trauma population are lacking.

Objective: The primary objective was to evaluate the effect of medication intensification on 30-day hospital readmissions in geriatric patients hospitalized for fall-related injuries.

Structural Analysis and Protein Binding of Cephalosporins.

Cephalosporins are a widely used subclass of β-lactam antibiotics that demonstrate variable protein binding independent of generation or antibiotic coverage. Prior work analyzed carbon 3 (C3) and carbon 7 (C7) substituents (locations of R and R groups respectively) for protein binding interactions. This study builds upon these results with statistical analysis of additional agents of the class.