Publications by authors named "Emily K Hodge"
Recent studies have established cefepime as an effective treatment option for AmpC beta-lactamase (AmpC) Enterobacterales; however, the efficacy of beta-lactam/beta-lactamase inhibitors is unclear. The objective of this study was to determine if piperacillintazobactamis an appropriate alternative to cefepime for the treatment of intra-abdominal infections (IAIs) secondary to AmpC-producing organisms. This multicenter, retrospective cohort study was conducted in hospitalized adults with an IAI caused by an AmpC-producing organism and received either cefepime or piperacillin-tazobactam for definitive treatment after a source control procedure.
View Article and Find Full Text PDFBackground: Benzodiazepines are the gold standard for treatment of alcohol withdrawal, yet the selection of a preferred benzodiazepine is limited due to a lack of comparative studies.
Objectives: The primary objective of this study was to compare the efficacy and safety of injectable lorazepam (LZP) and diazepam (DZP) in the treatment of severe alcohol withdrawal syndrome (AWS).
Methods: Retrospective cohort study of adult patients admitted to an intensive care unit with a primary diagnosis of AWS.
Article Synopsis
- The study investigates the effectiveness and safety of two sedatives, propofol and midazolam, in patients with acute respiratory distress syndrome (ARDS) who are on continuous infusion neuromuscular blocking agents.
- A total of 109 mechanically ventilated patients were analyzed, showing no significant difference in the time required to wean them off mechanical ventilation between the two sedatives.
- However, patients treated with propofol experienced a faster emergence from sedation after the neuromuscular blocker was stopped, suggesting it may be a preferable option for these patients.
Background: Clinician preferences and practices regarding appropriate vasopressin use in light of its increased acquisition cost secondary to rebranding has not been evaluated or described since the most recent iteration of the Surviving Sepsis Campaign Guideline was published.
Objective: To assess vasopressin cost containment initiatives and pharmacists' opinions regarding appropriate vasopressin use.
Methods: A scenario-based survey was distributed to critical care and emergency medicine pharmacists.
Background: Fixed-dose vasopressin is an adjunctive therapy to norepinephrine (NE) to raise mean arterial pressure (MAP) and decrease NE requirements in patients with septic shock. It is unknown if weight affects hemodynamic response to vasopressin or if a weight-based vasopressin strategy is superior to fixed dosing.
Objective: The primary objective was to evaluate effect of body weight on response to vasopressin as measured by change in MAP 1 hour post-vasopressin initiation.