Publications by authors named "Emily H Y Wong"

Article Synopsis
  • - The study investigated how adverse childhood experiences (ACEs) affect depression treatment outcomes in patients receiving repetitive transcranial magnetic stimulation (rTMS) therapies, specifically deep TMS and intermittent theta burst stimulation.
  • - Data from 99 patients indicated that while the average patient reported 2.4 ACEs, no significant differences in depression improvement were observed based on ACE scores, except for a slight early improvement in symptoms.
  • - Despite initial findings of a quicker response in patients with higher ACEs, the study concluded that ACEs should not deter the use of rTMS for treating depression, as they didn’t significantly affect long-term outcomes.
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Background: Numerous neuromodulatory therapies are currently under investigation or in clinical use for the treatment of psychiatric conditions.

Objective/hypothesis: We sought to catalogue past and present human research studies on psychiatric neuromodulation and identify relevant trends in this field.

Methods: ClinicalTrials.

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Background: Chronic pain is a debilitating condition that imposes a tremendous burden on health-care systems around the world. While frontline treatments for chronic pain involve pharmacological and psychological approaches, neuromodulation can be considered for treatment-resistant cases. Neuromodulatory approaches for pain are diverse in both modality and target and their mechanism of action is incompletely understood.

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Obsessive-compulsive disorder is a debilitating and often refractory psychiatric disorder. Magnetic resonance-guided focused ultrasound is a novel, minimally invasive neuromodulatory technique that has shown promise in treating this condition. We investigated the relationship between lesion location and long-term outcome in patients with obsessive-compulsive disorder treated with focused ultrasound to discern the optimal lesion location and elucidate the efficacious network underlying symptom alleviation.

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