Publications by authors named "Emily Ginn"

Article Synopsis
  • Gallstone ileus is a rare type of intestinal blockage characterized by the Rigler's triad, which includes small bowel obstruction, air in the biliary tract, and an obstructing gallstone, though not all cases display these signs.
  • In this case study, a 71-year-old man experienced abdominal pain, constipation, and distension, leading to the discovery of a long-standing gallstone in his small bowel, initially seen 4 years earlier on imaging.
  • Surgical intervention involved laparoscopic removal of the gallstone, which was found encased in fecal material, and the patient made a successful recovery without complications.
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Flexible heteroarotinoids (Flex-Hets) are compounds with promising anti-cancer activities. SHetA2, a first-generation Flex-Het, has been shown to inhibit the growth of cervical, head and neck, kidney, lung, ovarian, prostate, and breast cancers. However, SHetA2's high lipophilicity, limited selectivity, low oral bioavailability, and complicated synthesis has led to the development of second-generation compounds, such as 1-(1-(naphthalen-1-yl)ethyl)-3-(4-nitrophenyl) thiourea or SL-1-09.

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