Publications by authors named "Emily Ferguson Mason"
Article Synopsis
- The study compared the International Consensus (ICC) and World Health Organization (WHO5) classifications for myeloid diseases involving TP53 mutations, reviewing 188 cases.
- A significant 64% of cases were classified differently between the two systems, particularly due to ICC's inclusion of complex karyotype (CK) as a marker for biallelic TP53 inactivation.
- The findings show that TP53-mutated acute myeloid leukemia (AML) has distinct characteristics and worse survival compared to non-mutated cases, suggesting the need for better classification in future systems to recognize these differences.
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