Publications by authors named "Emily Crawley"
Article Synopsis
- Conventional channel-based microfluidic platforms are commonly used to create phospholipid nanostructures like liposomes, but they face scalability issues.
- A vortex fluidic device (VFD) offers a solution by using a thin film microfluidic approach, enabling the production of ~110 nm diameter liposomes through a high-yield, continuous flow process.
- The VFD can also facilitate the labeling of liposomes and study their stability and behavior under shear stress, revealing that ~110 nm liposomes are typically the most stable structures formed through self-assembly, similar to exosome sizes.
The aim of this study was to (1) describe accelerometer-assessed physical behaviours by chronotype, and (2) examine the association between chronotype and accelerometer-assessed physical behaviours in a cohort of adolescent girls. Chronotype (single question) and physical behaviours (GENEActiv accelerometer on the non-dominant wrist) were assessed in 965 adolescent girls (13.9 ± 0.
View Article and Find Full Text PDFMixing immiscible liquids typically requires the use of auxiliary substances including phase transfer catalysts, microgels, surfactants, complex polymers and nano-particles and/or micromixers. Centrifugally separated immiscible liquids of different densities in a 45° tilted rotating tube offer scope for avoiding their use. Micron to submicron size topological flow regimes in the thin films induce high inter-phase mass transfer depending on the nature of the two liquids.
View Article and Find Full Text PDFIn peptide production, oxidative sulfitolysis can be used to protect the cysteine residues during purification, and the introduction of a negative charge aids solubility. Subsequent controlled reduction aids in ensuring correct disulfide bridging. In vivo, these problems are overcome through interaction with chaperones.
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