Publications by authors named "Emily C Wirtz"

Article Synopsis
  • BIA-ALCL is a rare type of lymphoma linked primarily to textured breast implants, typically showing up years later as a fluid buildup near the implant.
  • Estimates indicate that the incidence might be as high as one in 3300 for patients with specific textured implants by Allergan, with 688 total reported cases worldwide as of February 2019.
  • A new case is presented of a woman who developed BIA-ALCL after transitioning from textured tissue expanders to smooth round implants, highlighting the potential risk associated even with smooth implants following textured ones.
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Background: Approximately 80% of patients with osteosarcoma harbor subclinical pulmonary micrometastases at diagnosis. Conventional chemotherapy includes methotrexate, doxorubicin, and cisplatin (MAP); however, this regimen and thus overall survival (60%-70%) have remained largely unchanged for 30 years. It therefore is necessary to identify novel therapeutics targeting the metastatic progression of osteosarcoma.

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