Publications by authors named "Emily C Rutledge"
Objective: To compare the rates of surgical site infection (SSI) after hysterectomy using vaginal antisepsis with chlorhexidine gluconate (CHG) versus povidone-iodine (PI).
Data Sources: PubMed, Embase, and Clinicaltrials.gov databases were queried from January 1, 1985 through Dec 7, 2023.
Pain Related to Intradetrusor BotulinumtoxinA: A Randomized Clinical Trial.
Urogynecology (Phila)
March 2024
Importance: OnabotulinumtoxinA (BTX-A) is an effective treatment for overactive bladder (OAB), but few studies have been done to evaluate injection techniques.
Objective: The primary objective was to evaluate procedural discomfort between 2 commonly used injection techniques for BTX-A.
Study Design: This was a single-blinded, randomized clinical trial of women undergoing injection of 100 U BTX-A for idiopathic OAB.
Article Synopsis
- This study aimed to investigate how race and socioeconomic status affect the rate of complications in patients undergoing pelvic organ prolapse (POP) repair.
- The analysis of 172,483 patients revealed that Black, Hispanic, and lower-income individuals faced higher risks for certain postoperative complications but had lower odds for some intraoperative issues compared to white patients with higher incomes.
- Ultimately, the findings highlight significant healthcare disparities, suggesting nonwhite patients with lower socioeconomic status are more vulnerable to postoperative complications, while white patients with higher socioeconomic status experience more intraoperative complications.
Health Care Disparities in Surgical Management of Pelvic Organ Prolapse: A Contemporary Nationwide Analysis.
Female Pelvic Med Reconstr Surg
April 2022
Objectives: Our objective was to compare the rate of native tissue repair (NTR) versus sacrocolpopexy (SCP) and reconstructive (RECON) versus obliterative repair (OBR) for the treatment of pelvic organ prolapse (POP), evaluating for health care disparities based on race, socioeconomic, and geographic factors.
Methods: The National Inpatient Sample database was queried for patients older than 18 years undergoing POP surgery from 2008 to 2018. Baseline demographics, comorbidity index, socioeconomic, and hospital variables were extracted.
Understanding the genetic and molecular mechanisms of ovarian cancer has been the focus of research efforts working toward the greater goal of improving cancer therapy for patients with residual disease after initial treatment with conventional surgery and neoadjuvant chemotherapy. The focus of this review will be centered on new therapeutic strategies based on Cancer Stem Cells studies of chemoresistant subpopulations, the prevention of metastasis, and individualized therapy in order to find the most successful combination of treatments to effectively treat human ovarian cancer. We reviewed recent literature (1993-2011) of novel treatment approaches to ovarian cancer stem cells.
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