Chronic Inflammation and γδ T Cells.

The epithelial tissues of the skin, lungs, reproductive tract, and intestines are the largest physical barriers the body has to protect against infection. Epithelial tissues are woven with a matrix of immune cells programed to mobilize the host innate and adaptive immune responses. Included among these immune cells are gamma delta T lymphocytes (γδ T cells) that are unique in their T cell receptor usage, location, and functions in the body.

Rational use of blood tests in the evaluation of rheumatic diseases.

Many blood tests used in the evaluation of rheumatic diseases are non-specific and should not be ordered and interpreted in isolation. False positive results can lead to inappropriate therapies with serious adverse events while false negatives may steer the provider to incorrect diagnoses. Relying on blood tests alone without considering the clinical context should be avoided.