Publications by authors named "Emily Bloomfield"
Breast cancer-related lymphedema is a lifelong disease associated with decreased quality of life and increased healthcare costs. Evidence supports early detection and prompt treatment through prospective surveillance models.
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- Breast cancer-related lymphedema (BCRL) is a common risk after axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SLNB), but existing prediction models have limitations such as not considering race and providing inaccurate risk assessments for SLNB patients.* -
- The study aimed to develop simple and accurate preoperative and postoperative models to predict BCRL risk, focusing on women who underwent ALND or SLNB at Memorial Sloan Kettering Cancer Center and the Mayo Clinic from 1999 to 2020.* -
- Out of 1882 women studied, 11.6% developed BCRL, with Black women showing a significantly higher occurrence; the new
Objective: To conduct a randomized controlled trial (RCT) on the efficacy of immediate lymphatic reconstruction (ILR) for decreasing the incidence of breast cancer-related lymphedema (BCRL) after axillary lymph node dissection (ALND).
Background: Despite encouraging results in small studies, an appropriately powered RCT on ILR has not been performed.
Methods: Women undergoing ALND for breast cancer were randomized in the operating room 1:1 to either ILR, if technically feasible, or no ILR (control).
Background: Lung delivery of plasmid DNA encoding the CFTR gene complexed with a cationic liposome is a potential treatment option for patients with cystic fibrosis. We aimed to assess the efficacy of non-viral CFTR gene therapy in patients with cystic fibrosis.
Methods: We did this randomised, double-blind, placebo-controlled, phase 2b trial in two cystic fibrosis centres with patients recruited from 18 sites in the UK.