Synopsis of recent research by authors named "Emily A Dickie"
- Emily A Dickie's recent research primarily focuses on targeting metabolic processes in protozoan parasites, specifically in combating leishmaniasis and trypanosomiasis, through chemical and genetic approaches, seeking new therapeutic options in the face of growing drug resistance.
- Her studies emphasize the role of sphingolipid metabolism, particularly the inositol phosphorylceramide synthase (IPCS), as a promising target for novel anti-leishmanial drugs, highlighting the draw of drug repurposing strategies such as identifying clemastine fumarate as a potential treatment.
- Additionally, Dickie investigates the impact of genetic mutations on lysosomal protein expression in Parkinson's disease, demonstrating significant interactions that may provide insights into degenerative processes and potential therapeutic avenues for neurodegenerative diseases.
