Publications by Emilio Itamar F Campos

Publications by authors named "Emilio Itamar F Campos"

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Non-genetic factors and polymorphisms in genes CYP2C9 and VKORC1: predictive algorithms for TTR in Brazilian patients on warfarin.

Marcus Fernando S Praxedes Maria Auxiliadora P Martins Aline O M Mourão Karina B Gomes Edna A Reis Emílio Itamar F Campos

Eur J Clin Pharmacol

February 2020

Purpose: This study was designed to evaluate the association of non-genetic factors and polymorphisms CYP2C9*2 (rs1799853), CYP2C9*3 (rs1075910), and VKORC1-G1639A (rs9923231) with time in therapeutic range (TTR), and to build a regression model to predict the quality of oral anticoagulation control in a sample of Brazilian patients.

Methods: This is a retrospective cohort study developed at an anticoagulation clinic of a university hospital. Overall, 312 patients were included.

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- Emilio Itamar F Campos focuses on the impact of both genetic polymorphisms and non-genetic factors on the efficacy of anticoagulation therapy, specifically in the context of warfarin treatment among Brazilian patients.
- His 2020 study investigates the association of specific gene variants (CYP2C9*2, CYP2C9*3, and VKORC1-G1639A) with the time in therapeutic range (TTR), which is critical for effective anticoagulation management.
- The research aims to develop predictive algorithms to improve oral anticoagulation control, based on data collected from a cohort of 312 patients treated in an anticoagulation clinic, contributing valuable insights for personalized medicine in thrombosis management.

Publications by authors named "Emilio Itamar F Campos"

Non-genetic factors and polymorphisms in genes CYP2C9 and VKORC1: predictive algorithms for TTR in Brazilian patients on warfarin.

Synopsis of recent research by authors named "Emilio Itamar F Campos"