Publications by authors named "Emilio Farinas"
Article Synopsis
- The study explores how genetic factors contribute to alcohol dependence, highlighting that high alcohol consumption and alcohol dependence have different genetic correlations with other psychiatric traits.
- Researchers analyzed data from 524 alcohol-dependent patients and 729 controls, calculating polygenic risk scores (PRS) to assess risks associated with alcohol use and various psychiatric disorders.
- Findings indicate that both general psychopathology (via the polygenic p factor) and high alcohol consumption are associated with alcohol dependence, suggesting that genetic risks can be divided into different components affecting this condition.
Genetic susceptibility to substance use disorders (SUDs) is partially shared between substances. Heritability of any substance dependence, estimated as 54%, is partly explained by additive effects of common variants. Comorbidity between SUDs and other psychiatric disorders is frequent.
View Article and Find Full Text PDFGenetics plays an important role in alcohol abuse/dependence. Its heritability has been estimated as 45-65%. Rare copy number variations (CNVs) have been confirmed as relevant genetic factors in other neuropsychiatric disorders, such as autism spectrum disorders, schizophrenia, epilepsy, or Tourette syndrome.
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