Activity of Estafietin and Analogues on and .

Sesquiterpene lactones are naturally occurring compounds mainly found in the Asteraceae family. These types of plant metabolites display a wide range of biological activities, including antiprotozoal activity and are considered interesting structures for drug discovery. Four derivatives were synthesized from estafietin (), isolated from (Asteraceae): 11βH,13-dihydroestafietin (), epoxyestafietin ( and ), 11βH,13-methoxyestafietin, () and 11βH,13-cianoestafietin.

Chemical composition and antifungal activity of essential oils from , , and against toxigenic and species.

Essential oils from aerial parts of and were analysed by GC-MS and their antifungal activities were assayed on toxigenic and species. Sabinene (27.6 ± 0.

Chemical composition and antifungal activity of essential oils from medicinal plants of Kazakhstan.

The composition of essential oils from leaves of Kazakhstan medicinal plants was analysed by GC-MS. The major compounds identified were 1,8-cineole (34.2%), myrcene (19.

Chemical composition and antimicrobial activity of essential oils from Acantholippia deserticola, Artemisia proceriformis, Achillea micrantha and Libanotis buchtormensis against phytopathogenic bacteria and fungi.

Essential oils from aerial parts of Acantholippia deserticola, Artemisia proceriformis, Achillea micrantha and Libanotis buchtormensis were analysed by GC-MS. The major compounds identified were β-thujone (66.5 ± 0.

Antifungal activity of 4-hydroxy-3-(3-methyl-2-butenyl)acetophenone against Candida albicans: evidence for the antifungal mode of action.

The main secondary metabolite of Senecio nutans is 4-hydroxy-3-(3-methyl-2-butenyl)acetophenone (4HMBA). The antifungal activity of this compound and three derivatives was assessed using Candida albicans. 4HMBA exhibited the highest antifungal activity among the assayed compounds.