Publications by authors named "Emilie Hill"

Article Synopsis
  • Smoking worsens periodontal disease and changes the bacteria found below the gumline, but how these changes contribute to disease progression is unclear.
  • A study observed 233 gum sites from smokers and non-smokers over 6-12 months, revealing that smokers had a more diverse microbiome at shallower probing depths, but this difference diminished at deeper depths.
  • Certain bacteria linked to disease progression were found more often in smokers, indicating that smoking may lead to harmful changes in gum bacteria that promote the development of periodontal disease.
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Article Synopsis
  • The subgingival microbiome is a stable system in healthy individuals, but variations exist over time and between different sites in the mouth.
  • Researchers sampled 251 subgingival samples from five healthy individuals over 6-12 months to analyze these variations and found significant differences in microbiome composition between individuals and sites.
  • Despite differences, the microbiome at specific sites was stable over time, suggesting that sampling individual sites is crucial for understanding the healthy subgingival microbiome's composition and function.
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Objective: We evaluate diagnostic accuracy of the ARCHITECT chemiluminescent immunoassay (CIA) screening test in pregnancy, and evaluate pregnancy outcomes among screen-positive women.

Study Design: Samples from routine prenatal rapid plasma reagin (RPR) tests were collected between June 22 and August 18, 2017 and frozen. Samples were batch-tested with the Abbott ARCHITECT syphilis TP immunoassay (CIA, index test).

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Background: Intra-abdominal abscesses are localized collections of pus, which generally arise from a breach in the normal mucosal defense barrier that allows bacteria from gastrointestinal tract, and less commonly from the gynecologic or urinary tract, to induce inflammation, resulting in an infection. The microbiology of these abscesses is usually polymicrobial, associated with the primary disease process. However, the microbial identity, diversity and richness in intra-abdominal abscesses have not been well characterized, due in part to the difficulty in cultivating commensal organisms using standard culture-based techniques.

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A 22-year-old female with sickle cell disease presented with fevers, bilateral knee pain, and lethargy. Laboratory data revealed a leukocytosis and lactic acidosis. Blood and synovial fluid cultures grew a non-toxin-producing strain of .

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A 37-year-old woman with a history of type II diabetes and Crohn's disease, status postcholecystectomy, presented with a >2-week history of cramping abdominal pain, nausea, non-bloody/non-bilious emesis and, later, diarrhoea. A flexible sigmoidoscopy was performed, revealing that 'a segmental pseudomembrane was found from rectum to sigmoid colon'. Clostridium difficile PCR on the stool was repeated twice and resulted negative both times.

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