Publications by authors named "Emilie Gauchotte"
Objective: To evaluate the perinatal outcome associated with severe and isolated intrauterine growth restriction (IUGR) diagnosed before 25 weeks and to describe factors related to fetal death.
Methods: This retrospective study included singleton pregnancies with an estimated fetal weight (EFW) ≤ 3rd centile between 21 + 0 and 24 + 6 weeks' gestation referred between 2013 and 2020. All fetuses with morphological or chromosomal abnormalities were excluded.
Article Synopsis
- Tranexamic acid (TXA) after cesarean delivery may reduce blood loss and transfusions, but it doesn’t significantly help with other hemorrhage-related issues, making its routine use uncertain.
- The study aimed to see if TXA is effective in preventing blood loss specifically for women with multiple pregnancies undergoing cesarean deliveries.
- Results showed no significant difference in blood loss between women receiving TXA and those on placebo, indicating that TXA may not be beneficial in this high-risk group.
Background: Prophylactic administration of tranexamic acid has been associated with reduced postpartum blood loss after cesarean delivery in several small trials, but evidence of its benefit in this clinical context remains inconclusive.
Methods: In a multicenter, double-blind, randomized, controlled trial, we assigned women undergoing cesarean delivery before or during labor at 34 or more gestational weeks to receive an intravenously administered prophylactic uterotonic agent and either tranexamic acid (1 g) or placebo. The primary outcome was postpartum hemorrhage, defined as a calculated estimated blood loss greater than 1000 ml or receipt of a red-cell transfusion within 2 days after delivery.
Predictors of successful manual rotation for occiput posterior positions.
Int J Gynaecol Obstet
February 2019
Objective: To identify predictors of the success of manual rotation of fetuses in an occiput posterior position.
Methods: A prospective, observational, single-center study included all women with a singleton pregnancy at term with a fetus in an occiput posterior position for whom manual rotation was attempted from December 1, 2013, to April 30, 2015 at a tertiary care maternity unit in Nancy, France. Occiput posterior position was confirmed by ultrasonography, and success of manual rotation was defined by the occiput anterior position of the fetus after the attempt.
Introduction: The aim of this study was to assess the impact of tamponade when uterotonic agents fail, on the need for surgery or interventional radiology.
Material And Methods: All women who received sulprostone for postpartum hemorrhage were retrospectively compared over two periods [December 2008 to December 2010 without use of tamponade (period 1) and June 2011 to June 2013 with use of tamponade (period 2)] in the case of sulprostone failure (STROBE compliant retrospective cohort study). During period 2, interventional radiology or surgery was used only in the case of tamponade failure.
Introduction: Metaplastic carcinomas of the breast are rare and form a heterogenic group of tumors, characterized by the presence of squamous or sarcomatoid differentiation.
Patient And Methods: In 23 cases, we study the main histoprognostic features, hormonal status, and the expression of HER2, CK5/6, CK14, p63, EGFR, beta-catenin, MUC1 and E-cadherin, the expression of this seven last antigens being also studied in nodal metastases.
Results: The different metaplastic types are spindle cell carcinoma (35%), squamous cell carcinoma (26%), osteo- or chondrosarcomatoid (11%) or mixed type (26%).