Wound tissue remodeling by latex exudate of : A plant species used in Brazilian folk medicine.

This work investigated the healing properties of proteins extracted of latex (HdLP) on excisional wounds. Cell toxicity of HdLP was investigated carried out in murine fibroblasts after incubation with HdLP (12.5-100 μg/ml).

Disseminated hematogenous tuberculosis in puerperium-case report.

Although tuberculosis (TB) is relatively common in pregnancy and puerperium, its disseminated form is a rare event, with potential lethal maternal and fetal outcomes. Due to the infrequency and lack of knowledge of most physicians about the various manifestations of the disease, the diagnosis is often overlooked, and treatment postponed, resulting in a high death rate. We report a fatal case of disseminated tuberculosis in the puerperium, with lung, brain, liver and uterine involvement.

A phytomodulatory hydrogel with enhanced healing effects.

The healing performance of a hydrogel composed of hemicelluloses extracted from seeds of Caesalpinia pulcherrima (Fabaceae) and mixed with phytomodulatory proteins obtained from the latex of Calotropis procera was characterized on excisional wounds. The hydrogel did not induce dermal irritability. When topically used on excisional wounds, the hydrogel enhanced healing by wound contraction.

Postmortem Findings for 7 Neonates with Congenital Zika Virus Infection.

Postmortem examination of 7 neonates with congenital Zika virus infection in Brazil revealed microcephaly, ventriculomegaly, dystrophic calcifications, and severe cortical neuronal depletion in all and arthrogryposis in 6. Other findings were leptomeningeal and brain parenchymal inflammation and pulmonary hypoplasia and lymphocytic infiltration in liver and lungs. Findings confirmed virus neurotropism and multiple organ infection.